Hypertension and increased body mass index, common concomitants of the weight gain induced by antipsychotic medications, are associated with decreased immediate and delayed memory in schizophrenia. Friedman et al. found in their study that these neurocognitive deficits are associated with decreased psychosocial function in patients with schizophrenia. Addressing hypertension and obesity in patients may therefore improve disabling neuro-cognitive deficits that are not otherwise amenable to treatment. Dr. Henry Nasrallah states in an editorial that prevention of weight loss is critical for optimal therapeutic response for schizophrenia.